Dr. Li-Li Hsiao is a clinical fellow in the Division of Nephrology at the Brigham & Women's Hospital and Harvard Medical School. Her research focus is on the elucidation of gene expression profiles using oligonucleotide microarrays. The experimental approaches she is using includes functional genomics, creation and analyses of human tissues from normal and various disease states (HuGE Index Project, www.HuGEIndex.org). The disease states include acute renal failure, diabetic nephropathy, polycystic kidney disease, ovarian cancer, Aden carcinoma of lung, mesothelioma, and Alzheimer disease among others. For this work, she has collaborated with over 20 faculty members from various universities throughout the country. The ultimate goals of her research is to establish a database of gene expression profiles for normal human tissues, understand the pathogenesis of the diseases and to develop better prediction, prevention and intervention strategies. This work has been published and is part of the Human Gene Expression database (www.hugeindex.org) which can be downloaded as a resource for investigators and to which information may also be uploaded.