Protein Domain Families: Databases and Search Tools

• InterPro - integration of Pfam, PRINTS, PROSITE, SWISS-PROT + TrEMBL
• PROSITE - database of protein families and domains
• Pfam - alignments and hidden Markov models covering many common protein domains
• SMART - analysis of domains in proteins
• ProDom - protein domain database
• PRINTS Database - groups of conserved motifs used to characterise protein families
• Blocks - multiply aligned ungapped segments corresponding to the most highly conserved regions of proteins
• Protein Domain Profile Analysis @ BMERC - search a library of profiles with a protein sequence
• TIGRFAMs - yet more protein families based on Hidden Markov Models